Candida intermedia induced central line infection in an infant: A case report

Authors

  • Ali Alsarhan al jalila children's hospital
  • Hesham Obeidat Aljalila children's hospital

DOI:

https://doi.org/10.46831/jpas.v2i2.170

Keywords:

Central venous catheter, Staphylococcus aureus, Infection

Abstract

Background: Central venous catheter (CVC) carries a risk of infection, particularly with prolonged use of antibiotics and parenteral nutrition (PN). The most common causative agent is Staphylococcus aureus but other bacteria and fungi can cause infection as well.

Case Presentation: This is a case of an 11-month-old male PN-dependent infant with a complex medical history who developed a fungal infection of the central line due to Candida intermedia. Despite displaying in-vitro sensitivity to Fluconazole, the infection ultimately required treatment with Caspofungin and the removal of the venous catheter for successful clearance and full recovery.

Conclusion: This case underscores the importance of tailoring treatment based on both anti-fungal sensitivity and clinical response, emphasizing the importance of CVC removal in achieving infection clearance

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References

Weiner LM, Webb AK, Limbago B, Dudeck MA, Patel J, Kallen AJ, et al. Antimicrobial-resistant pathogens associated with healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2011–2014. Inf Cont Hosp Epidemiol.. 2016; 37:1288–301.

Hasejima N, Kamei K, Matsubayashi M, Kawabe R, Shimura C, Hijikata N, et al. The first case of bloodstream infection by Candida intermedia in Japan: the importance of molecular identification. J Inf Chemother [Internet]. 2011; 17:555–8. Available from: https://pubmed.ncbi.nlm.nih.gov/21302127/.

Ruan SY, Chien JY, Hou YC, Hsueh PR. Catheter-related fungemia caused by Candida intermedia. Int J inf Dis [Internet]. 2010; 14:e147-9. Available from: https://pubmed.ncbi.nlm.nih.gov/19497773/

Kullberg BJ, Arendrup MC. Invasive Candidiasis. New Eng J Med. 2015; 373:1445–56

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Published

2023-12-08

How to Cite

1.
Alsarhan A, Obeidat H. Candida intermedia induced central line infection in an infant: A case report. J Pediatr Adolesc Surg [Internet]. 2023Dec.8 [cited 2024Dec.9];2(2). Available from: http://jpedas.org/ojs/index.php/jpedas/article/view/170

Issue

Vol. 2 No. 2 (2021): Journal of Pediatric and Adolescent Surgery

Section

Case Report

License

Copyright (c) 2023 Ali Alsarhan, Hesham Obeidat

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