Inflammatory myofibroblastic tumor of caecum presenting as recurrent intussusception: A case report
DOI:
https://doi.org/10.46831/jpas.v1i2.59Keywords:
Caecum, Desmin, Immunohistochemistry, Inflammatory tumor, Myofibroblastic tumor, Pseudotumor, Recurrent intussusception, Spindle cell tumor, VimentinAbstract
Background: Inflammatory myofibroblastic tumor is an uncommon tumor. It commonly affects the lung but it can be found anywhere in the body.
Case Report: We are reporting a case of caecal mass presenting as recurrent intussusceptions. Histopathology and immunohistochemistry confirmed it to be an inflammatory myofibroblastic tumor of caecum. Immunohistochemistry of tumor cells were positive for vimentin, smooth muscle actin, MIB 1, and CD 45 in lymphoid cells in the stroma of the tumor.
Conclusion: Recurrent intussusception should be kept as one of the differential diagnosis in patient with caecal mass with recurrent abdominal pain. Inflammatory myofibroblastic tumor of the caecum is unusual in paediatric patients and may present as recurrent intussusception.
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Applegate KE. Intussusception in children: evidence-based diagnosis and treatment. Pediatr Radiol. 2009; 39 (suppl 2): S140-143.
Zhang Y, Zou W, Zhang Y, Ye W, Chen X, Liu Q, et al. Reducing Antibiotic Use for Young Children with Intussusception following Successful Air Enema Reduction. PLoS One. 2015; 10(11): e0142999.
Singh AP, Gupta AK, Barolia DK, Ansari M. Post-Operative Intussusception in a Child after Pseudo Cyst of Pancreas Excision. National J Health Sci. 2018; 3 (2):61-66.
Ito Y, Kusakawa I, Murata Y, Ukiyama E, Kawase H. Kamagata S, et al. Japanese guidelines for the management of intussusception in children, 2011. Pediatr Int. 2012; 54 (6): 948-958.
Tothova Z, Wagner AJ. Anaplastic lymphoma kinase-directed therapy in inflammatory myofibroblastic tumors. Curr Opin Oncol. 2012; 24(4):409–413.
Lourenço SV, Boggio P, Simonsen Nico MM. Inflammatory myofibroblastic tumor of the tongue: report of an unusual case in a teenage patient. Dermatol Online J. 2012; 18(5):6.
Pannain VL, Passos JV, Rocha Filho A, Villela-Nogueira C, Caroli-Bottino A. Agressive inflammatory myofibroblastic tumor of the liver with underlying schistosomiasis: A case report. World J Gastroenterol 2010; 16(33): 4233-4236.
Rao RN, Ranjan P, Singla N, Pandey R. Inflammatory myofibroblastic tumor of the urinary bladder diagnosed by anaplastic lymphoma kinase immunostaining. Urol Ann. 2012; 4 (2):115-118.
Takeuchi K, Choi YL, Togashi Y, Soda M, Hatano S, Inamura K, et al. KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res. 2009; 15 (9) :3143-3149.
Binmadi NO, Packmanb H, Papadimitriouc JC, Scheper M. Oral inflammatory myofibroblastic tumor: case report and review of literature. Open Dent J. 2011; 5:66-70.
Umiker WO, Iverson L. Post inflammatory tumors of the lung; report of four cases simulating xanthoma, fibroma, or plasma cell tumor. J Thorac Surg. 1954; 28 (1):55–63.
Li J, Liu F, Wang Z, Liu Q, Wang Y, Zhou Q, et al. Inflammatory pseudotumor of the esophagus: GI image. J Gastrointest Surg. 2010; 14:195–198.
Ladd AP, Grosfeld JL. Gastrointestinal tumors in children and adolescents. Semin Pediatr Surg. 2006; 15 (1):37–47.
Mehra SK, Barolia DK, Gupta AK, Chaturvedi V. Childhood Intussusception: Timely management leads to decreased surgical risk. Int J Innov Res Med Sci 2018; 3: 1672-1674.
Zhang Y, Dong ZJ, Zhi XY, Liu L, Hu M. Inflammatory myofibroblastic tumor in lung with osteopulmonary arthropathy. Chin Med J (Engl). 2009;122(24):3094-3096.
Sanders BM, West KW, Gingalewski C, Engum S, Davis M, Grosfeld JL. Inflammatory pseudotumor of the alimentary tract: clinical and surgical experience. J Pediatr Surg. 2001; 36 (1) :169–173.
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Copyright (c) 2021 Dr.Dinesh Kumar Barolia, Aditya Pratap Singh, Dr. Harsha Vinod Bathia, Vipal H Parmar, Bhavana Asit Mehta, Shraddha Mehta
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